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Isoniazid
is used to prevent active tuberculosis in persons who have an abnormal skin test for tuberculosis or in combination with other drugs for the treatment of active tuberculosis. Isoniazid, or INH, is an anti-bacterial drug that has been used to prevent and to treat tuberculosis since 1952. Tuberculosis is an infectious diseased caused by a bacterium. Once the infection is acquired, it usually remains dormant in the lungs. Later, the infection may become active in the lungs and sometimes spreads throughout the body. Patients with a tuberculosis skin test that has recently become abnormal (demonstrating recent infection with tuberculosis) but a normal chest x-ray (demonstrating inactive infection) are given INH alone for 6-9 months. Patients with active infection on chest x-ray are given INH combined with other antituberculous drugs.

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